Recombinant Human IL-5
Catalog Number : 200-05
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.
Above 98% as determined by SDS-PAGE Analysis.
Guinea Pig, Mouse
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 106 units/mg.
MIPTEIPTS ALVKETLAL LSTHRTLLI ANETLRIPV PVHKNHQLC TEEIFQGIG TLESQTVQG GTVERLFKN LSLIKKYID GQKKKCGEE RRRVNQFLD YLQEFLGVM NTEWIIES
|Research Interest:||Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle|
|Cell Type:||B Cells, T Cells|
|Protein Cross Reactivity:||Guinea Pig, Mouse|