Recombinant Human IL-2
Catalog Number : 200-02
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.
Above 98% as determined by SDS-PAGE Analysis.
Dog, Monkey, Mouse, Rat
The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
MAPTSSSTK KTQLQLEHL LLDLQMILN GINNYKNPK LTRMLTFKF YMPKKATEL KHLQCLEEE LKPLEEVLN LAQSKNFHL RPRDLISNI NVIVLELKG SETTFMCEY ADETATIVE FLNRWITFC QSIISTLT
|Research Interest:||Adaptive Immunity, Stem Cell Research, Immunology, Cancer, Neurosciences, Inflammation, Proliferation and Cell Cycle, Metabolic Regulation and Diabetes|
|Cell Type:||B Cells, Macrophage / Monocyte, NK and NKT Cells, T Cells, T Regulatory Cells|
|Protein Cross Reactivity:||Dog, Monkey, Mouse, Rat|