Recombinant Human IL-17B
Catalog Number : 200-28
IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-α and IL-1β from cells of the monocyte lineage. Recombinant human IL-17B is a 36.6 kDa non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. Please Note: Results may vary with PBMC donors.
MQPRSPKSK RKGQGRPGP LAPGPHQVP LDLVSRMKP YARMEEYER NIEEMVAQL RNSSELAQR KCEVNLQLW MSNKRSLSP WGYSINHDP SRIPVDLPE ARCLCLGCV NPFTMQEDR SMVSVPVFS QVPVRRRLC PPPPRTGPC RQRAVMETI AVGCTCIF
|Research Interest:||Innate Immunity, Adaptive Immunity|
|Cell Type:||Macrophage / Monocyte, T Cells|
|Protein Cross Reactivity:||NULL|