Animal-Free Recombinant Murine IL-2
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues. Manufactured using all non-animal reagents.
Above 98% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
PTSSSTSSS TAEAQQQQQ QQQQQQQHL EQLLMDLQE LLSRMENYR NLKLPRMLT FKFYLPKQA TELKDLQCL EDELGPLRH VLDLTQSKS FQLEDAENF ISNIRVTVV KLKGSDNTF ECQFDDESA TVVDFLRRW IAFCQSIIS TSPQ
|Research Interest:||Adaptive Immunity, Immunology, Cancer, Neurosciences, Inflammation, Proliferation and Cell Cycle, Metabolic Regulation and Diabetes|
|Cell Type:||B Cells, Macrophage / Monocyte, NK and NKT Cells, T Cells, T Regulatory Cells|
|Protein Cross Reactivity:||Human|