Animal-Free Recombinant Human IL-17E

Grouped product items
SizePrice Qty
25µg
$215.00
100µg
$660.00
500µg
$1,980.00
1mg
$3,300.00
Catalog Number : AF-200-24

description

IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. Manufactured using all non-animal reagents.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
NULL
Biological Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.
AA Sequence
MYSHWPSCC PSKGQDTSE ELLRWSTVP VPPLEPARP NRHPESCRA SEDGPLNSR AISPWRYEL DRDLNRLPQ DLYHARCLC PHCVSLQTG SHMDPRGNS ELLYHNQTV FYRRPCHGE KGTHKGYCL ERRLYRVSL ACVCVRPRV MG
Research Interest:Inflammation
Application:FA
Protein Cross Reactivity:NULL
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