Recombinant Murine IFN-λ2
Catalog Number : 250-33
IFN-λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-λs uses a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-λ2 is a 19.8 kDa protein containing 175 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to activate STAT following receptor-ligand interaction.
MDPVPRATR LPVEAKDCH IAQFKSLSP KELQAFKKA KDAIEKRLL EKDMRCSSH LISRAWDLK QLQVQERPK ALQAEVALT LKVWENMTD SALATILGQ PLHTLSHIH SQLQTCTQL QATAEPKPP SRRLSRWLH RLQEAQSKE TPGCLEDSV TSNLFRLLT RDLKCVASG DQCV
|Protein Cross Reactivity:||Human, Virus|