Recombinant Murine IFN-λ2

Grouped product items
SizePrice Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 250-33

description

IFN-λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-λs uses a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-λ2 is a 19.8 kDa protein containing 175 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Human, Virus
Biological Activity
Determined by its ability to activate STAT following receptor-ligand interaction.
AA Sequence
MDPVPRATR LPVEAKDCH IAQFKSLSP KELQAFKKA KDAIEKRLL EKDMRCSSH LISRAWDLK QLQVQERPK ALQAEVALT LKVWENMTD SALATILGQ PLHTLSHIH SQLQTCTQL QATAEPKPP SRRLSRWLH RLQEAQSKE TPGCLEDSV TSNLFRLLT RDLKCVASG DQCV
Application:FA
Protein Cross Reactivity:Human, Virus
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