Recombinant Rat FGF-basic
Catalog Number : 400-29
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant rat FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.
Above 95% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells is ≤ 0.2 ng/ml corresponding to a specific activity of ≥5 x 106 units/mg.
PALPEDGGG AFPPGHFKD PKRLYCKNG GFFLRIHPD GRVDGVREK SDPHVKLQL QAEERGVVS IKGVCANRY LAMKEDGRL LASKCVTEE CFFFERLES NNYNTYRSR KYSSWYVAL KRTGQYKLG SKTGPGQKA ILFLPMSAK S
|Research Interest:||Stem Cell Research, Cancer, Angiogenesis, Inflammation, Proliferation and Cell Cycle|
|Cell Type:||Macrophage / Monocyte, Stem Cells, Endothelial Cells, Neurons|
|Protein Cross Reactivity:||NULL|