Recombinant Murine FGF-acidic
Catalog Number : 450-33A
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
Above 95% as determined by SDS-PAGE Analysis.
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 u
MFNLPLGNY KKPKLLYCS NGGHFLRIL PDGTVDGTR DRSDQHIQL QLSAESAGE VYIKGTETG QYLAMDTEG LLYGSQTPN EECLFLERL EENHYNTYT SKKHAEKNW FVGLKKNGS CKRGPRTHY GQKAILFLP LPVSSD
|Research Interest:||Stem Cell Research, Cancer, Angiogenesis, Neurosciences, Bone Biology, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells, Endothelial Cells|
|Protein Cross Reactivity:||NULL|