Recombinant Human KGF (FGF-7)
Catalog Number : 100-19
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
Above 95% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
CNDMTPEQM ATNVNCSSP ERHTRSYDY MEGGDIRVR RLFCRTQWY LRIDKRGKV KGTQEMKNN YNIMEIRTV AVGIVAIKG VESEFYLAM NKEGKLYAK KECNEDCNF KELILENHY NTYASAKWT HNGGEMFVA LNQKGIPVR GKKTKKEQK TAHFLPMAI T
|Research Interest:||Stem Cell Research, Angiogenesis, Proliferation and Cell Cycle|
|Protein Cross Reactivity:||Mouse, Rat|