Recombinant Human FGF-8

Grouped product items
Size Price Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 100-25

description

FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 95% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Chicken, Mouse, Rabbit, Rat
Biological Activity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
AA Sequence
MQVTVQSSP NFTQHVREQ SLVTDQLSR RLIRTYQLY SRTSGKHVQ VLANKRINA MAEDGDPFA KLIVETDTF GSRVRVRGA ETGLYICMN KKGKLIAKS NGKGKDCVF TEIVLENNY TALQNAKYE GWYMAFTRK GRPRKGSKT RQHQREVHF MKRLPRGHH TTEQSLRFE FLNYPPFTR SLRGSQRTW APEPR
Research Interest: Stem Cell Research, Cancer, Angiogenesis, Bone Biology, Proliferation and Cell Cycle
Cell Type: Stem Cells
Application: FA
Protein Cross Reactivity: Chicken, Mouse, Rabbit, Rat
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