Recombinant Human FGF-6
Catalog Number : 100-30
FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.
Above 95% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
MGTRANNTL LDSRGWGTL LSRSRAGLA GEIAGVNWE SGYLVGIKR QRRLYCNVG IGFHLQVLP DGRISGTHE ENPYSLLEI STVERGVVS LFGVRSALF VAMNSKGRL YATPSFQEE CKFRETLLP NNYNAYESD LYQGTYIAL SKYGRVKRG SKVSPIMTV THFLPRI
|Research Interest:||Stem Cell Research, Cancer, Angiogenesis, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells|
|Protein Cross Reactivity:||NULL|