Recombinant Human FGF-4
Catalog Number : 100-31
description
FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.
Additional Information
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Source:
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E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity:
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Mouse, Rat
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Biological Activity
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The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
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AA Sequence
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GRGGAAAPT APNGTLEAE LERRWESLV ALSLARLPV AAQPKEAAV QSGAGDYLL GIKRLRRLY CNVGIGFHL QALPDGRIG GAHADTRDS LLELSPVER GVVSIFGVA SRFFVAMSS KGKLYGSPF FTDECTFKE ILLPNNYNA YESYKYPGM FIALSKNGK TKKGNRVSP TMKVTHFLP RL
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| Research Interest: | Stem Cell Research, Angiogenesis, Proliferation and Cell Cycle |
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| Cell Type: | Stem Cells |
| Application: | FA |
| Protein Cross Reactivity: | Mouse, Rat |