Recombinant Human FGF-21
Catalog Number : 100-42
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of βKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes. Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.
Above 90% as determined by SDS-PAGE Analysis.
FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.
MHPIPDSSP LLQFGGQVR QRYLYTDDA QQTEAHLEI REDGTVGGA ADQSPESLL QLKALKPGV IQILGVKTS RFLCQRPDG ALYGSLHFD PEACSFREL LLEDGYNVY QSEAHGLPL HLPGNKSPH RDPAPRGPA RFLPLPGLP PALPEPPGI LAPQPPDVG SSDPLSMVG PSQGRSPSY AS
|Research Interest:||Stem Cell Research, Angiogenesis, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells|
|Protein Cross Reactivity:||NULL|