Recombinant Human FGF-18

Grouped product items
SizePrice Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 100-28

description

FGF-18 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant E.coli derived human FGF-18 is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from c-terminal truncation of the full length protein.

Additional Information

Source:
E. Coli
Purity:
Above 95% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Mouse, Rat
Biological Activity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
AA Sequence
AEENVDFRI HVENQTRAR DDVSRKQLR LYQLYSRTS GKHIQVLGR RISARGEDG DKYAQLLVE TDTFGSQVR IKGKETEFY LCMNRKGKL VGKPDGTSK ECVFIEKVL ENNYTALMS AKYSGWYVG FTKKGRPRK GPKTRENQQ DVHFMKRYP KGQPELQKP FKYTTVTKR SR
Research Interest:Stem Cell Research, Angiogenesis, Bone Biology, Proliferation and Cell Cycle
Application:FA
Protein Cross Reactivity:Mouse, Rat
© BioGems International, Inc. All rights reserved.