Animal-Free Recombinant Murine FGF-basic
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues. Manufactured using all non-animal reagents.
Above 95% as determined by SDS-PAGE Analysis.
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥ 1 x 10
PALPEDGGA AFPPGHFKD PKRLYCKNG GFFLRIHPD GRVDGVREK SDPHVKLQL QAEERGVVS IKGVCANRY LAMKEDGRL LASKCVTEE CFFFERLES NNYNTYRSR KYSSWYVAL KRTGQYKLG SKTGPGQKA ILFLPMSAK S
|Research Interest:||Stem Cell Research, Cancer, Angiogenesis, Neurosciences, Inflammation, Proliferation and Cell Cycle|
|Cell Type:||Macrophage / Monocyte, Stem Cells, Endothelial Cells, Neurons|
|Protein Cross Reactivity:||Rabbit|