Recombinant Human G-CSF
Catalog Number : 300-23
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
TPLGPASSL PQSFLLKCL EQVRKIQGD GAALQEKLC ATYKLCHPE ELVLLGHSL GIPWAPLSS CPSQALQLA GCLSQLHSG LFLYQGLLQ ALEGISPEL GPTLDTLQL DVADFATTI WQQMEELGM APALQPTQG AMPAFASAF QRRAGGVLV ASHLQSFLE VSYRVLRHL AQP
|Research Interest:||Innate Immunity, Stem Cell Research, Cancer, Angiogenesis, Inflammation, Metabolic Regulation and Diabetes|
|Cell Type:||Macrophage / Monocyte, Stem Cells, Endothelial Cells|
|Protein Cross Reactivity:||Monkey,Mouse, Pig|