Recombinant Human G-CSF
Catalog Number : 300-23
description
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | Monkey,Mouse, Pig |
Biological Activity | The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. |
AA Sequence | TPLGPASSL PQSFLLKCL EQVRKIQGD GAALQEKLC ATYKLCHPE ELVLLGHSL GIPWAPLSS CPSQALQLA GCLSQLHSG LFLYQGLLQ ALEGISPEL GPTLDTLQL DVADFATTI WQQMEELGM APALQPTQG AMPAFASAF QRRAGGVLV ASHLQSFLE VSYRVLRHL AQP |
| Research Interest: | Innate Immunity, Stem Cell Research, Cancer, Angiogenesis, Inflammation, Metabolic Regulation and Diabetes |
|---|---|
| Cell Type: | Macrophage / Monocyte, Stem Cells, Endothelial Cells |
| Application: | FA |
| Protein Cross Reactivity: | Monkey,Mouse, Pig |