Recombinant Human BMP-5

Grouped product items
Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$780.00
500µg
$2,340.00
1mg
$3,900.00
Catalog Number : 120-39

description

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs.  BMP-5 is expressed in the nervous system, lung and liver.  It is a known regulator for dendritic growth in sympathetic neurons.  BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein.  Recombinant human BMP-5 is a 15.6 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

Additional Information

Source:
CHO cells
Purity:
Above 95% as determined by SDS-PAGE Analysis.
Cross Reactivity:
NULL
Biological Activity
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.
AA Sequence
AANKRKNQN RNKSSSHQD SSRMSSVGD YNTSEQKQA CKKHELYVS FRDLGWQDW IIAPEGYAA FYCDGECSF PLNAHMNAT NHAIVQTLV HLMFPDHVP KPCCAPTKL NAISVLYFD DSSNVILKK YRNMVVRSC GCH
Research Interest: Apoptosis, Neurosciences, Bone Biology, Proliferation and Cell Cycle
Application: FA
Protein Cross Reactivity: NULL
© BioGems International, Inc. All rights reserved.