Recombinant Human BMP-4
Catalog Number : 120-05
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Above 97% as determined by SDS-PAGE Analysis.
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
HHSQRARKK NKNCRRHSL YVDFSDVGW NDWIVAPPG YQAFYCHGD CPFPLADHL NSTNHAIVQ TLVNSVNSS IPKACCVPT ELSAISMLY LDEYDKVVL KNYQEMVVE GCGCR
|Research Interest:||Stem Cell Research, Apoptosis, Angiogenesis, Bone Biology, Proliferation and Cell Cycle|
|Protein Cross Reactivity:||NULL|