Recombinant Murine gAcrp30
Catalog Number : 450-27
gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant murine gAcrp30 is a 16.6 kDa protein consisting of 145 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED50 for this effect is ≤ 15 µg/ml.
MKGEPGEAA YMYRSAFSV GLETRVTVP NVPIRFTKI FYNQQNHYD GSTGKFYCN IPGLYYFSY HITVYMKDV KVSLFKKDK AVLFTYDQY QEKNVDQAS GSVLLHLEV GDQVWLQVY GDGDHNGLY ADNVNDSTF TGFLLYHDT N
|Research Interest:||Metabolic Regulation and Diabetes|
|Protein Cross Reactivity:||NULL|