Recombinant Human gAcrp30/Adipolean
Catalog Number : 450-21
gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant human gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to inhibit the proliferation of murine M1 cells. The expected ED50 for this effect is 1.0-3.0 μg/ml.
MKGEPGEGA YVYRSAFSV GLETYVTIP NMPIRFTKI FYNQQNHYD GSTGKFHCN IPGLYYFAY HITVYMKDV KVSLFKKDK AMLFTYDQY QENNVDQAS GSVLLHLEV GDQVWLQVY GEGERNGLY ADNDNDSTF TGFLLYHDT N
|Research Interest:||Metabolic Regulation and Diabetes|
|Protein Cross Reactivity:||Mouse, Rat|