Recombinant Murine SDF-1α (CXCL12)
Catalog Number : 250-20A
description
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1α is a 7.9 kDa protein containing 68 amino acid residues.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | Human, Rat |
Biological Activity | Determined by its ability to chemoattract human peripheral blood monocytes using a concentration of 50-100 ng/ml. |
AA Sequence | KPVSLSYRC PCRFFESHI ARANVKHLK ILNTPNCAL QIVARLKNN NRQVCIDPK LKWIQEYLE KALNK |
Research Interest: | Stem Cell Research, Cancer, Neurosciences, Inflammation |
---|---|
Cell Type: | B Cells, T Cells, Stem Cells |
Application: | FA |
Protein Cross Reactivity: | Human, Rat |