Recombinant Human SDF-1α (CXCL12)
Catalog Number : 300-28A
description
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | Mouse, Rat |
Biological Activity | Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80 ng/ml. |
AA Sequence | KPVSLSYRC PCRFFESHV ARANVKHLK ILNTPNCAL QIVARLKNN NRQVCIDPK LKWIQEYLE KALNK |
| Research Interest: | Stem Cell Research, Cancer, Neurosciences, Inflammation |
|---|---|
| Cell Type: | B Cells, T Cells, Stem Cells |
| Application: | FA |
| Protein Cross Reactivity: | Mouse, Rat |