Animal-Free Recombinant Human SDF-1β (CXCL12)
Catalog Number : AF-300-28B
description
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues. Manufactured using all non-animal reagents.
Additional Information
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Source:
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E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity:
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NULL
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Biological Activity
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Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20-80 ng/ml.
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AA Sequence
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KPVSLSYRC PCRFFESHV ARANVKHLK ILNTPNCAL QIVARLKNN NRQVCIDPK LKWIQEYLE KALNKRFKM
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| Research Interest: | Innate Immunity, Stem Cell Research, Cancer, Neurosciences, Inflammation |
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| Cell Type: | B Cells, T Cells, Stem Cells |
| Application: | FA |
| Protein Cross Reactivity: | NULL |