Recombinant Human MIP-3 (CCL23)
Catalog Number : 300-29
description
MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | NULL |
Biological Activity | Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml. |
AA Sequence | RVTKDAETE FMMSKLPLE NPVLLDRFH ATSADCCIS YTPRSIPCS LLESYFETN SECSKPGVI FLTKKGRRF CANPSDKQV QVCMRMLKL DTRIKTRKN |
| Cell Type: | Macrophage / Monocyte, T Cells |
|---|---|
| Application: | FA |
| Protein Cross Reactivity: | NULL |