Recombinant Murine JE/MCP-1 (CCL2)
Catalog Number : 250-10
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
QPDAVNAPL TCCYSFTSK MIPMSRLES YKRITSSRC PKEAVVFVT KLKREVCAD PKKEWVQTY IKNLDRNQM RSEPTTLFK TASALRSSA PLNVKLTRK SEANASTTF STTTSSTSV GVTSVTVN
|Research Interest:||Immunology, Cancer, Angiogenesis, Neurosciences, Inflammation|
|Cell Type:||Macrophage / Monocyte, T Cells, Dendritic Cells|
|Protein Cross Reactivity:||Bacteria, Human|