Recombinant Human MCP-1 (CCL2)
Catalog Number : 300-04
description
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | Bacteria, Chicken, Hamster, Monkey, Mouse, Rat |
Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml. |
AA Sequence | QPDAINAPV TCCYNFTNR KISVQRLAS YRRITSSKC PKEAVIFKT IVAKEICAD PKQKWVQDS MDHLDKQTQ TPKT |
| Research Interest: | Innate Immunity, Adaptive Immunity, Cancer, Angiogenesis, Neurosciences, Inflammation |
|---|---|
| Cell Type: | Macrophage / Monocyte, NK and NKT Cells, T Cells, Dendritic Cells |
| Application: | FA |
| Protein Cross Reactivity: | Bacteria, Chicken, Hamster, Monkey, Mouse, Rat |