Recombinant Human Eotaxin-3 (CCL26)
Catalog Number : 300-48
Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract human CCR3/HEK 293 cells. The maximum activity was achieved at 2ug/ml.
TRGSDISKT CCFQYSHKP LPWTWVRSY EFTSNSCSQ RAVIFTTKR GKKVCTHPR KKWVQKYIS LLKTPKQL
|Research Interest:||Immunology, Proliferation and Cell Cycle|
|Cell Type:||Macrophage / Monocyte, T Cells, Endothelial Cells|
|Protein Cross Reactivity:||Mouse|