Recombinant Human Eotaxin-2 (CCL24)
Catalog Number : 300-33
Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.
VVIPSPCCM FFVSKRIPE NRVVSYQLS SRSTCLKGG VIFTTKKGQ QFCGDPKQE WVQRYMKNL DAKQKKASP RARAVA
|Research Interest:||Adaptive Immunity, Proliferation and Cell Cycle|
|Cell Type:||Macrophage / Monocyte, T Cells, Stem Cells, Dendritic Cells|
|Protein Cross Reactivity:||NULL|