Animal-Free Recombinant Murine SCF
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Manufactured using all non-animal reagents.
Above 98% as determined by SDS-PAGE Analysis.
Human, Monkey, Rat
The ED50 as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.
MKEICGNPV TDNVKDITK LVANLPNDY MITLNYVAG MDVLPSHCW LRDMVIQLS LSLTTLLDK FSNISEGLS NYSIIDKLG KIVDDLVLC MEENAPKNI KESPKRPET RSFTPEEFF SIFNRSIDA FKDFMVASD TSDCVLSST LGPEKDSRV SVTKPFMLP PVA
|Research Interest:||Stem Cell Research, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells|
|Protein Cross Reactivity:||Human, Monkey, Rat|