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Recombinant Murine MDC (CCL22)



Catalog Number : 250-23

Description

MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Human
 
Biological Activity
Determined by its ability to chemoattract human activated lymphocytes using a concentration of 10.0-100.0 ng/ml.
 
AA Sequence
GPYGANVED SICCQDYIR HPLPSRLVK EFFWTSKSC RKPGVVLIT VKNRDICAD PRQVWVKKL LHKLS
Research Interest: Innate Immunity
Cell Type: B Cells, Monocytes and Macrophages, NK and NKT Cells, T Cells, Dendritic Cells
Protein Cross Reactivity: Human

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00