Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Recombinant Murine LIGHT



Catalog Number : 315-12

Description

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Human
 
Biological Activity
Testing in progress.
 
AA Sequence
MRLHQRLGD IVAHLPDGG KGSWEKLIQ DQRSHQANP AAHLTGANA SLIGIGGPL LWETRLGLA FLRGLTYHD GALVTMEPG YYYVYSKVQ LSGVGCPQG LANGLPITH GLYKRTSRY PKELELLVS RRSPCGRAN SSRVWWDSS FLGGVVHLE AGEEVVVRV PGNRLVRPR DGTRSYFGA FMV
Research Interest: Innate Immunity, Apoptosis, Cancer, Inflammation
Cell Type: Monocytes and Macrophages
Protein Cross Reactivity: Human

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00