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Recombinant Murine IL-9



Catalog Number : 219-19

Description

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant murine IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Human
 
Biological Activity
The ED50 as determined by the dose-dependent proliferation of human MO7e cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/mg.
 
AA Sequence
MQRCSTTWG IRDTNYLIE NLKDDPPSK CSCSGNVTS CLCLSVPTD DCTTPCYRE GLLQLTNAT QKSRLLPVF HRVKRIVEV LKNITCPSF SCEKPCNQT MAGNTMSFL KSLLGTFQK TEMQRQKSR P
Research Interest: Adaptive Immunity, Cancer, Proliferation and Cell Cycle
Cell Type: T Cells
Protein Cross Reactivity: Human

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00