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Recombinant Murine IL-31



Catalog Number : 210-31

Description

IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Testing in Progress.
 
AA Sequence
MTCSLSFGA PISKEDLRT TIDLLKQES QDLYNNYSI KQASGMSAD ESIQLPCFS LDREALTNI SVIIAHLEK VKVLSENTV DTSWVIRWL TNISCFNPL NLNISVPGN TDESYDCKV FVLTVLKQF SNCMAELQA KDNTTC
Research Interest: Innate Immunity, Adaptive Immunity, Inflammation
Cell Type: T Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00