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Recombinant Murine IL-2



Catalog Number : 212-12

Description

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Human
 
Biological Activity
The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
 
AA Sequence
PTSSSTSSS TAEAQQQQQ QQQQQQQHL EQLLMDLQE LLSRMENYR NLKLPRMLT FKFYLPKQA TELKDLQCL EDELGPLRH VLDLTQSKS FQLEDAENF ISNIRVTVV KLKGSDNTF ECQFDDESA TVVDFLRRW IAFCQSIIS TSPQ
Research Interest: Adaptive Immunity, Immunology, Cancer, Neurosciences, Inflammation, Proliferation and Cell Cycle, Metabolic Regulation and Diabetes
Cell Type: B Cells, Monocytes and Macrophages, NK and NKT Cells, T Cells, Treg cells
Protein Cross Reactivity: Human

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$560.00
500µg
$1,680.00
1mg
$2,800.00