Recombinant Murine G-CSF
Catalog Number : 250-05
description
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues.
Additional Information
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Source:
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E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity:
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NULL
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Biological Activity
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The ED50 was determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a s
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AA Sequence
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MVPLVTVSA LPPSLPLPR SFLLKSLEQ VRKIQASGS VLLEQLCAT YKLCHPEEL VLLGHSLGI PKASLSGCS SQALQQTQC LSQLHSGLC LYQGLLQAL SGISPALAP TLDLLQLDV ANFATTIWQ QMENLGVAP TVQPTQSAM PAFTSAFQR RAGGVLAIS YLQGFLETA RLALHHLA
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| Research Interest: | Innate Immunity, Stem Cell Research, Cancer, Angiogenesis, Inflammation, Metabolic Regulation and Diabetes |
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| Cell Type: | Macrophage / Monocyte, Stem Cells, Endothelial Cells |
| Application: | FA |
| Protein Cross Reactivity: | NULL |