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Recombinant Murine Eotaxin-2 (CCL24)



Catalog Number : 250-22

Description

Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3 kDa protein containing 93 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100 ng/ml.
 
AA Sequence
VTIPSSCCT SFISKKIPE NRVVSYQLA NGSICPKAG VIFITKKGH KICTDPKLL WVQRHIQKL DAKKNQPSK GAKAVRTKF AVQRRRGNS TEV
Research Interest: Immunology
Cell Type: Monocytes and Macrophages, T Cells, Stem Cells, Dendritic Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00