Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Recombinant Human WISP-1



Catalog Number : 120-18

Description

WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. WISP-1 is a β catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 346 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cysteine knot-like (CTCK) domain.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Mouse, Rat
 
Biological Activity
The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 1.0-3.0 µg/ml.
 
AA Sequence
TALSPAPTT MDFTPAPLE DTSSRPQFC KWPCECPPS PPRCPLGVS LITDGCECC KMCAQQLGD NCTEAAICD PHRGLYCDY SGDRPRYAI GVCAQVVGV GCVLDGVRY NNGQSFQPN CKYNCTCID GAVGCTPLC LRVRPPRLW CPHPRRVSI PGHCCEQWV CEDDAKRPR KTAPRDTGA FDAVGEVEA WHRNCIAYT SPWSPCSTS CGLGVSTRI SNVNAQCWP EQESRLCNL RPCDVDIHT LIKAGKKCL AVYQPEASM NFTLAGCIS TRSYQPKYC GVCMDNRCC IPYKSKTID VSFQCPDGL GFSRQVLWI NACFCNLSC RNPNDIFAD LESYPDFSE IAN
Research Interest: Cancer, Bone Biology
Protein Cross Reactivity: Mouse, Rat

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$780.00
500µg
$2,340.00
1mg
$3,900.00