Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Recombinant Human TL-1A



Catalog Number : 310-23

Description

TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to stimulate IFN-γ production by human PBMC using a concentration range of 10.0-100.0 ng/ml. Note: Results may vary with PBMC donors.
 
AA Sequence
QLRAQGEAS VQFQALKGQ EFAPSHQQV YAPLRADGD KPRAHLTVV RQTPTQHFK NQFPALHWE HELGLAFTK NRMNYTNKF LLIPESGDY FIYSQVTFR GMTSECSEI RQAGRPNKP DSITVVITK VTDSYPEPT QLLMGTKSV CEVGSNWFQ PIYLGAMFS LQEGDKLMV NVSDISLVD YTKEDKTFF GAFLL
Research Interest: Apoptosis, Angiogenesis
Cell Type: Endothelial Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00