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Recombinant Human NT-4



Catalog Number : 450-04

Description

NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
 
AA Sequence
GVSETAPAS RRGELAVCD AVSGWVTDR RTAVDLRGR EVEVLGEVP AAGGSPLRQ YFFETRCKA DNAEEGGPG AGGGGCRGV DRRHWVSEC KAKQSYVRA LTADAQGRV GWRWIRIDT ACVCTLLSR TGRA
Research Interest: Stem Cell Research, Neurosciences, Metabolic Regulation and Diabetes
Cell Type: Neurons
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00