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Recombinant Human MDC (69 a.a.) (CCL22)



Catalog Number : 300-36A

Description

MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Hamster, Mouse
 
Biological Activity
Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
 
AA Sequence
GPYGANMED SVCCRDYVR YRLPLRVVK HFYWTSDSC PRPGVVLLT FRDKEICAD PRVPWVKMI LNKLSQ
Research Interest: Innate Immunity
Cell Type: B Cells, Monocytes and Macrophages, NK and NKT Cells, T Cells, Dendritic Cells
Protein Cross Reactivity: Hamster, Mouse

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00