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Recombinant Human IP-10 (CXCL10)



Catalog Number : 300-12

Description

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Bacteria, Monkey, Mouse,Leech, Human + Hamster
 
Biological Activity
Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml.
 
AA Sequence
VPLSRTVRC TCISISNQP VNPRSLEKL EIIPASQFC PRVEIIATM KKKGEKRCL NPESKAIKN LLKAVSKER SKRSP
Research Interest: Immunology, Angiogenesis, Neurosciences, Inflammation, Proliferation and Cell Cycle
Cell Type: Monocytes and Macrophages
Protein Cross Reactivity: Bacteria, Monkey, Mouse,Leech, Human + Hamster

Availability: In stock

Size Price Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00