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Recombinant Human IL-9



Catalog Number : 200-09

Description

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.0 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
The ED50 as determined by the dose-dependent proliferation of human M07e cells was ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
 
AA Sequence
MQGCPTLAG ILDINFLIN KMQEDPASK CHCSANVTS CLCLGIPSD NCTRPCFSE RLSQMTNTT MQTRYPLIF SRVKKSVEV LKNNKCPYF SCEQPCNQT TAGNALTFL KSLLEIFQK EKMRGMRGK I
Research Interest: Adaptive Immunity, Cancer, Proliferation and Cell Cycle
Cell Type: T Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00