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Recombinant Human IL-5



Catalog Number : 200-05

Description

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Guinea Pig, Mouse
 
Biological Activity
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 106 units/mg.
 
AA Sequence
MIPTEIPTS ALVKETLAL LSTHRTLLI ANETLRIPV PVHKNHQLC TEEIFQGIG TLESQTVQG GTVERLFKN LSLIKKYID GQKKKCGEE RRRVNQFLD YLQEFLGVM NTEWIIES
Research Interest: Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle
Cell Type: B Cells, T Cells
Protein Cross Reactivity: Guinea Pig, Mouse

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$860.00
500µg
$2,580.00
1mg
$4,300.00