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Recombinant Human IL-33



Catalog Number : 200-33

Description

Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Mouse
 
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/
 
AA Sequence
SITGISPIT EYLASLSTY NDQSITFAL EDESYEIYV EDLKKDEKK DKVLLSYYE SQHPSNESG DGVDGKMLM VTLSPTKDF WLHANNKEH SVELHKCEK PLPDQAFFV LHNMHSNCV SFECKTDPG VFIGVKDNH LALIKVDSS ENLCTENIL FKLSET
Research Interest: Immunology, Inflammation
Protein Cross Reactivity: Mouse

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
50µg
$624.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00