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Recombinant Human IL-20



Catalog Number : 200-20

Description

IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to activate STAT following receptor ligand interaction.
 
AA Sequence
MLKTLNLGS CVIATNLQE IRNGFSEIR GSVQAKDGN IDIRILRRT ESLQDTKPA NRCCLLRHL LRLYLDRVF KNYQTPDHY TLRKISSLA NSFLTIKKD LRLCHAHMT CHCGEEAMK KYSQILSHF EKLEPQAAV VKALGELDI LLQWMEETE
Research Interest: Stem Cell Research, Immunology, Inflammation, Proliferation and Cell Cycle
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00