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Recombinant Human IL-19



Catalog Number : 200-19

Description

IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to activate STAT following receptor-ligand interaction.
 
AA Sequence
MLRRCLIST DMHHIEESF QEIKRAIQA KDTFPNVTI LSTLETLQI IKPLDVCCV TKNLLAFYV DRVFKDHQE PNPKILRKI SSIANSFLY MQKTLRQCQ EQRQCHCRQ EATNATRVI HDNYDQLEV HAAAIKSLG ELDVFLAWI NKNHEVMSS A
Research Interest: Innate Immunity, Inflammation
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00