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Recombinant Human IL-17B



Catalog Number : 200-28

Description

IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-α and IL-1β from cells of the monocyte lineage. Recombinant human IL-17B is a 36.6 kDa non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. Please Note: Results may vary with PBMC donors.
 
AA Sequence
MQPRSPKSK RKGQGRPGP LAPGPHQVP LDLVSRMKP YARMEEYER NIEEMVAQL RNSSELAQR KCEVNLQLW MSNKRSLSP WGYSINHDP SRIPVDLPE ARCLCLGCV NPFTMQEDR SMVSVPVFS QVPVRRRLC PPPPRTGPC RQRAVMETI AVGCTCIF
Research Interest: Innate Immunity, Adaptive Immunity
Cell Type: Monocytes and Macrophages, T Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00