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Recombinant Human IFN-β



Catalog Number : 300-02BC

Description

Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFNβ. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNα contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNβ is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNβ has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.

*Human IFN-β(Catalog Number 300-02BC) has replaced Human IFN-β(Catalog Number 300-02B)

Additional Information

Source:
CHO cells
 
Purity:
Above 95% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Monkey, Mouse
 
Biological Activity
Assay #1:Measured by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 20-30 ng/ml.

Assay #2: Determined by its ability to stimulate the prol
 
AA Sequence
MSYNLLGFL QRSSNFQCQ KLLWQLNGR LEYCLKDRM NFDIPEEIK QLQQFQKED AALTIYEML QNIFAIFRQ DSSSTGWNE TIVENLLAN VYHQINHLK TVLEEKLEK EDFTRGKLM SSLHLKRYY GRILHYLKA KEYSHCAWT IVRVEILRN FYFINRLTG YLRN
Research Interest: Immunology, Cancer, Neurosciences
Protein Cross Reactivity: Monkey, Mouse

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$780.00
500µg
$2,340.00
1mg
$3,900.00