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Recombinant Human FGF-6



Catalog Number : 100-30

Description

FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 95% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
 
AA Sequence
MGTRANNTL LDSRGWGTL LSRSRAGLA GEIAGVNWE SGYLVGIKR QRRLYCNVG IGFHLQVLP DGRISGTHE ENPYSLLEI STVERGVVS LFGVRSALF VAMNSKGRL YATPSFQEE CKFRETLLP NNYNAYESD LYQGTYIAL SKYGRVKRG SKVSPIMTV THFLPRI
Research Interest: Stem Cell Research, Cancer, Angiogenesis, Proliferation and Cell Cycle
Cell Type: Stem Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00