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Recombinant Human Eotaxin (CCL11)



Catalog Number : 300-21

Description

Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and along Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung, and in allergic reactions. Recombinant human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Mouse, Human + Hamster, Human + Guinea Pig
 
Biological Activity
Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/ml.
 
AA Sequence
GPASVPTTC CFNLANRKI PLQRLESYR RITSGKCPQ KAVIFKTKL AKDICADPK KKWVQDSMK YLDQKSPTP KP
Research Interest: Immunology
Cell Type: Monocytes and Macrophages, T Cells, Endothelial Cells
Protein Cross Reactivity: Mouse, Human + Hamster, Human + Guinea Pig

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00